Mefenamic Acid: Uses, Alternatives, and What You Need to Know

When you’re dealing with sharp menstrual cramps or stubborn muscle pain, Mefenamic Acid, a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain and inflammation. Also known as Ponstel, it works by blocking the body’s pain signals at the source, not just masking them. Unlike acetaminophen, which only eases pain, Mefenamic Acid actually cuts down swelling—making it a go-to for period pain, dental discomfort, or even mild arthritis flare-ups.

It’s not the only option, though. Other NSAIDs, a class of drugs that reduce inflammation and relieve pain like ibuprofen or naproxen do similar things, but Mefenamic Acid has a stronger focus on gynecological pain. Studies show it’s especially effective for heavy periods, with some women reporting relief within an hour. But it’s not for everyone—people with stomach ulcers, kidney issues, or heart conditions need to be careful. And while it’s often sold over-the-counter in some countries, in others, you need a prescription. That’s because long-term or high-dose use can raise risks of bleeding or high blood pressure.

Many people don’t realize that menstrual cramps, pain caused by uterine contractions during menstruation aren’t just a normal part of being a woman—they can be a sign of something deeper like endometriosis. Mefenamic Acid helps manage the symptoms, but if your cramps are getting worse or lasting longer than usual, it’s worth talking to a doctor. And if you’re looking for alternatives, options like hormonal birth control, heat therapy, or even acupuncture (as seen in related posts on urinary retention relief) can work alongside or instead of NSAIDs.

You’ll find posts here that compare pain relievers, explain how to avoid side effects, and even show you how to buy generic versions safely online. Some people use Mefenamic Acid for short-term relief, others for chronic pain. Either way, knowing how it stacks up against other drugs like ibuprofen or dicloxacillin (yes, even some antibiotics are used off-label for inflammation) helps you make smarter choices. This collection doesn’t just list drugs—it shows you how they fit into real life: what works, what doesn’t, and what to watch out for.