Acid Reflux Medication: What Works, What to Avoid, and How to Choose

When your chest burns after eating, you’re not just uncomfortable—you’re dealing with acid reflux medication, drugs designed to reduce stomach acid and ease symptoms of gastroesophageal reflux disease (GERD). Also known as heartburn medicine, these treatments range from over-the-counter antacids to prescription drugs that change how your body produces acid. It’s not just about popping a pill. The right choice depends on how often it happens, how bad it is, and what’s causing it in the first place.

Most people start with antacids, quick-acting chewables or liquids that neutralize stomach acid—think Tums or Rolaids. They help fast, but only for a few hours. If you’re dealing with daily symptoms, you might need something longer-lasting like H2 blockers, medications like ranitidine or famotidine that cut acid production at the source. These take longer to kick in but last longer. Then there are proton pump inhibitors, powerful drugs like omeprazole and esomeprazole that shut down acid production almost completely. These are the go-to for chronic GERD, but they’re not harmless. Long-term use can affect bone health, vitamin absorption, and even gut bacteria.

What you eat, when you eat, and how you sleep all play a role. Coffee, spicy food, and lying down after meals make acid reflux worse. Some people find relief just by changing habits—eating smaller meals, avoiding late-night snacks, or raising the head of their bed. But if you’ve tried that and still feel the burn, medication isn’t a sign of weakness—it’s a tool. The key is matching the right one to your pattern. Not everyone needs a PPI. Some do fine with an H2 blocker. Others need a mix. And some don’t need pills at all.

You’ll find posts here that compare different acid reflux meds side by side, explain how they really work, and show you what to watch for with long-term use. There’s no guesswork here—just clear, practical info on what’s safe, what’s effective, and what might be doing more harm than good. Whether you’re just starting out or have been managing this for years, you’ll find something that helps you take control.